Publications
2023
Eikemo M, Løseth GE, Carlyle M, Trøstheim M, Ernst G, Pazmandi C, Thompson M, Vezzani C, Meier IM, Johnstone T, Heilig M, Biele G, Leknes S (2023) Stress-enhanced opioid self-administration in healthy men: A randomized controlled experimental medicine study. [Preprint OSF ]
Carlyle M, Wit H de, Leknes S. Impact of childhood adversity on acute subjective effects of stimulant and opioid drugs: Evidence from placebo-controlled studies in healthy volunteers [Internet]. [Preprint OSF]
Løseth GE, Trøstheim M, Leknes S. (2023) Endogenous Mu-Opioid Modulation of Social Connection in Humans: A Systematic Review and Meta-Analysis. Preprint PsyArXiv
Marie Eikemo, Isabell M. Meier, Guro Engvig Løseth, Martin Trøstheim, Nikoline Ørstavik, Eira Nordeng Jensen, Eric Garland, Chantal Berna, Gernot Ernst, and Siri Leknes (2023). Opioid analgesic effects on subjective well-being in the operating theatre. Anaesthesia 2023-06-28 [Preprint PsyArXiv]
M Carlyle, M Kvande, IM Meier, M Trøstheim, K Buen, EN Jensen, G Ernst, S Leknes, M Eikemo (2023) Does childhood adversity alter opioid drug reward? A conceptual replication in outpatients before surgery. Addiction Research & Theory, 1-12
Isabell M Meier, Marie Eikemo, Martin Trøstheim, Kaja Buen, Eira Nordeng Jensen, Siri Gurandsrud Karlsen, Silje Endresen Reme, Chantal Berna, Siri Leknes, and Gernot Ernst (2023) Factors Associated with Use of Opioid Rescue Medication after Surgery. Regional Anesthesia and Pain Medicine [Preprint PsyArXiv]
M Scarth, LE Hauger, PM Thorsby, S Leknes, I Hullstein, LT Westlye, A Bjørnebekk (In press, Psychopharmacology). Supraphysiological testosterone levels from anabolic steroid use and reduced sensitivity to negative facial expressions in men. Preprint PsyArXiv
2022
Guro E Løseth, Marie Eikemo, Martin Trøstheim, Isabell M. Meier, Herman Bjørnstad, Anna Asratian, Claudia Pazmandi, Vegard Wathne Tangen, Markus Heilig, and Siri Leknes (2022) Stress Recovery with Social Support: A Dyadic Stress and Support Task. Psychoneuroendocrinology 146: 105949. [Preprint PsyArXiv]
U Sailer, S Leknes (2022) Meaning makes touch affective. Current Opinion in Behavioral Sciences 44, 101099
Trøstheim M, Eikemo M, Haaker J, Frost JJ, Leknes S (2022). Opioid Antagonism in Humans: A Primer on Optimal Dose and Timing for Central Mu-Opioid Receptor Blockade. Neuropsychopharmacology 48 (2), 299-307 [preprint BioArXiv]
S Leknes & LY Atlas (2022) Corrigendum to ‘Flawed methodology undermines conclusions about opioid-induced pleasure: implications for psychopharmacology’(Br J Anaesth 2020; 124: e29-e33) British Journal of Anaesthesia
A Parisi, HL Landicho, J Hudak, S Leknes, B Froeliger, EL Garland (2022). Emotional distress and pain catastrophizing predict cue-elicited opioid craving among chronic pain patients on long-term opioid therapy. Drug and Alcohol Dependence 233, 109361
C Skoglund, S Leknes, M Heilig (2022). The partial µ-opioid agonist buprenorphine in autism spectrum disorder: a case report. Journal of Medical Case Reports 16 (1), 1-6
2021
Marie Eikemo, Guro Løseth, and Siri Leknes (2021). Do endogenous opioids mediate or fine-tune human
pain relief? Pain 162(12), 2789-91. Link to preprint.
Isabell M. Meier, Marie Eikemo and Siri Leknes (2021). The role of mu-opioids for reward and threat processing in humans: Bridging the gap from preclinical to clinical opioid drug studies. Current Addiction Reports
S Henningsson, S Leknes, M Asperholm, M Eikemo, L Westberg (2021) A randomized placebo-controlled intranasal oxytocin study on first impressions and reactions to social rejection. Biological Psychology 164, 108164
B Laeng, L Garvija, G Løseth, M Eikemo, G Ernst, S Leknes. (2021) ‘Defrosting’ music chills with naltrexone: The role of endogenous opioids for the intensity of musical pleasure Consciousness and Cognition 90, 103105
2020
Unni Sulutvedt, Daniele Zavagno, Jamie Lubell, Siri Leknes, Sigrid A. de Rodez Benavent, Bruno Laeng. (2020) Brightness perception changes related to pupil size. Vision research. 178:41-47
Hovey D, Martens L, Laeng B, Leknes S, Westberg L. (2020) The effect of intranasal oxytocin on visual processing and salience of human faces. Translational Psychiatry. Sep 19;10(1):318. doi: 10.1038/s41398-020-00991-3.
Martin Trøstheim, Marie Eikemo, Remy Meir, Ingelin Hansen, Elisabeth Paul, Sara Liane Kroll, Eric L Garland & Siri Leknes (2020) Assessment of Anhedonia in Adults With and Without Mental Illness: A Systematic Review and Meta-analysis. JAMA Network Open 3 (8), e2013233-e2013233
2019
Siri Leknes & Lauren Y Atlas (2019). Flawed methodology undermines conclusions about opioid-induced pleasure: implications for psychopharmacology. British Journal of Anaesthesia
Lisa E Hauger, Dominic Sagoe, Anja Vaskinn, Espen A Arnevik, Siri Leknes, Marie L Jørstad & Astrid Bjørnebekk (2019). Anabolic androgenic steroid dependence is associated with impaired emotion recognition. Psychopharmacology 236 (9), 2667-2676
Eric L. Garland, Martin Trøstheim, Marie Eikemo and Siri Leknes (2019). Anhedonia in Chronic Pain and Prescription Opioid Misuse. Psychological Medicine 1- 12
2018
2017
Marie Eikemo, Guido Biele, Frode Willoch, Lotte Thomsen & Siri Leknes. (2017) Opioid modulation of value-based decision making in healthy humans, Neuropsychopharmacology [Supplementary materials]
2016
2015
2014
Chelnokova O, Laeng B, Eikemo M, Riegels J, Løseth G, Maurud H, Willoch F, Leknes S (2014) Rewards of Beauty: The Opioid System Mediates Social Motivation in Humans. Mol Psychiatry 19:746-747. [Supplementary materials]
Leknes S, Bastian B (2014) The benefits of pain. The Review in Philosophy and Psychology 5:57-70.
Leknes S, Bastian B (2014) How does pain affect eating and food pleasure? Pain 155:652-653. How does pain affect eating and food pleasure? Pain 155:652-653.
2013
2012
2011
Leknes S (2011) The pain modulatory cocktail. Scand J Pain 2:105-107. How does pain affect eating and food pleasure? Pain 155:652-653.
2010
Berna C, Leknes S, Holmes EA, Edwards RR, Goodwin GM, Tracey I (2010) Induction of depressed mood disrupts emotion regulation neurocircuitry and enhances pain unpleasantness. Biol Psychiatry 67:1083-1090. [Supplementary materials]
2008
Leknes S, Tracey I (2008) A common neurobiology for pain and pleasure. Nat Rev Neurosci 9:314-320.